United will face Arnett Gardens FC of Jamaica. The Jamaican club advanced with a 6-2 aggregate goals edge on SV Transvaal of Suriname. The preliminary series was tied at 1-1 after an opening game draw in Suriname. The return match was a rout, with Arnett Gardens posting an impressive 5-1 victory at home. Arnett Gardens and the Crew will play a two-game set beginning on April 3-5 and 10-12 in the Giants Cup quarterfinals.
Columbus will take on CD Saprissa of Costa Rica, who held a 5-1 edge after two matches against Alianza FC of El Salvador. The second match was a 0-0 draw, held in Costa Rica, as was the first match due to the earthquake damage in El Salvador. Attacker Rolando Fonseca, the all-time goal scoring leader among active Costa Rican internationals, leads Saprissa. United will face Saprissa in the Giants Cup quarterfinals on April 3-5 and 10-12.
The dates and times of the quarterfinal matches are yet to be determined. The two MLS clubs are currently slated to host the second legs in their respective quarterfinal series.