Stories
| Date | Teams | Time | Venue | Eastern Time |
|---|---|---|---|---|
| Sept. 12 | DC Hyper 3 - 0 Oranje FC | - | Prince George Community College; Largo, Md. | - |
| Sept. 12 | Naples United FC 5 - 1 SWFL SC | - | Seacrest Country Day School; Naples, Fla. | - |
| Sept. 12 | Florida Island United FC 2 - 3 Boca Jrs Miami FC | - | Oak Grove Park; Miami | - |
| Sept. 12 | Croatia Cleveland 1 (3) - 1 (4) Steel City FC (AET & PKs) | - | Mentor High School; Mentor, Ohio | - |
| Sept. 12 | Bowleys Athletic 4 - 1 MSI | - | Eastern Regional Park; Middle River, Md. | - |
| Sept. 12 | Florida Badgers FC 1 - 0 Red Force FC | - | Broward College; Pembroke Pines, Fla. | - |
| Sept. 12 | Swarm FC 5 - 1 Prima Football Club | - | Marathon Soccer Park; Austell, Ga. | - |
| Sept. 12 | Lansdowne Yonkers FC 1 - 0 New York Athletic Club | - | Tibbetts Park; Yonkers, N.Y. | - |
| Sept. 12 | Temecula FC 5 - 1 Problems FC | - | Chaparral High School; Temecula, Calif. | - |
| Sept. 12 | Chicago Strikers 1 (3) - 1 (4) Ethos United (AET & PKs) | - | Marmion Academy; Aurora, Ill. | - |
| Sept. 12 | STG Premier FC 5 - 0 Be Pro FC | - | Snow Canyon High School; St. George, Utah | - |
| Sept. 12 | Sin City Football Club 2 - 1 Las Vegas United Football Club | - | Mater Academy East; Las Vegas | - |
| Sept. 13 | Peachtree FC 4 - 5 Kalonji Pro-Profile | - | Mount Paran Christian School; Kennesaw, Ga. | - |
| Sept. 13 | Southern Indiana Guardians FC 1 - 3 Mockingbird Valley Premier (AET) | - | Woehrle Athletic Complex; Jeffersonville, Ind. | - |
| Sept. 13 | Five Rivers SC 1 - 4 SC Vistula Garfield | - | Joseph Medwick Park; Carteret, N.J. | - |
| Sept. 13 | Arlington SA Pro 0 - 2 Virginia Dream FC | - | Thomas Jefferson High School; Alexandria, Va. | - |
| Sept. 13 | Lorain County Leviathan FC 3 - 4 Akron City FC | - | ForeFront Field; Avon, Ohio | - |
| Sept. 13 | Doradus FC 2 - 1 Nova FC (AET) | - | West Springfield High School; West Springfield, Va. | - |
| Sept. 13 | Tennessee United Soccer Club 0 - 6 Tennessee Tempo FC | - | Drakes Creek Park; Hendersonville, Tenn. | - |
| Sept. 13 | UFA Lawrenceville 0 - 6 Terminus FC | - | Bay Creek Park; Loganville, Ga. | - |
| Sept. 13 | Timbers SC 0 - 6 FC Denver | - | David A. Lorenz Regional Park; Highlands Ranch, Colo. | - |
| Sept. 13 | Osner's FC 3 - 2 American Soccer Club New York | - | Floyd Bennett Sports Complex; Brooklyn, N.Y. | - |
| Sept. 13 | Yinz United 10 - 1 Patuxent FA | - | Langley High School; McLean, Va. | - |
| Sept. 13 | FC Kanks 1 - 2 Shark Coast FC | - | XL Lake Nona; Orlando, Fla. | - |
| Sept. 13 | StrikerZ DFW 1 - 4 FORO SC | - | McKinney Boyd High School; McKinney, Texas | - |
| Sept. 13 | Peak Eleven FC 4 - 0 Colorado Rovers | - | Pinnacle Athletic Complex; Thornton, Colo. | - |
| Sept. 19 | Buckhead SC 1 - 3 Potros FC | - | Agnes Scott College; Decatur, Ga. | - |
